Chitosan Oligosaccharides Coupling Inhibits Bacterial Biofilm-Related Antibiotic Resistance against Florfenicol

Antibiotic Resistance Related to Biofilm Formation in Klebsiella pneumoniae

The Gram-negative opportunistic pathogen, Klebsiella pneumoniae, is responsible for causing a spectrum of community-acquired and nosocomial infections and typically infects patients with indwelling medical devices, especially urinary catheters, on which this microorganism is able to grow as a biofilm. The increasingly frequent acquisition of antibiotic resistance by K. pneumoniae strains has gi...

Bacterial antibiotic resistance pdf

Two page summaries of cross-cutting and bacteriaspecific antibiotic resistance topics. The first section provides context and an overview of antibiotic resistance.Antimicrobial resistance: global report on surveillance. Resistance to antibacterial drugs in selected bacteria of international concern. Previously harmful agents that is known today as antimicrobial resistance. Currently antimicrobi...

Lysozyme Associated Liposomal Gentamicin Inhibits Bacterial Biofilm

Bacteria on living or inert surfaces usually form biofilms which make them highly resistant to antibiotics and immune clearance. Herein, we develop a simple approach to overcome the above conundrum through lysozyme-associated liposomal gentamicin (LLG). The association of lysozyme to the surface of liposomes can effectively reduce the fusion of liposomes and undesirable payload release in regul...

antibiotic prescription and bacterial resistance

Chitosan Oligosaccharides Attenuates Oxidative-Stress Related Retinal Degeneration in Rats

This study investigated the therapeutic potential and mechanisms of chitosan oligosaccharides (COS) for oxidative stress-induced retinal diseases. Retinal oxidative damage was induced in Sprague-Dawley rats by intravitreal injection of paraquat (PQ). Low-dose (5 mg/kg) or high-dose (10 mg/kg) COS or PBS was intragastrically given for 14 days after PQ injection. Electroretinograms were performed...